Please note: This is for information only.

Refer to local guidelines for treatment recommendations.

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• Includes the Coliform bacilli eg E. Coli, Klebsiella sp, Enterobacter sp, Salmonella sp and the Pseudomonas, Acinetobacters, Neisseria sp. and Bacteroides.

Main clinical infections:

• Abdominal and urinary tract infections.
• Coliforms and Pseudomonas can be responsible for hospital-acquired pneumonia particularly ventilator-associated.

Usually sensitive to:

• Quinolones (ciprofloxacin, levofloxacin) (except Bacteroides)
• Aminoglycosides (gentamicin, tobramycin, amikacin) (except Neisseria sp).
• The 2nd and 3rd generation cephalosporins (Pseudomonas and Acinetobacter only sensitive to the 3rd generation cephalosporin ceftazidime.)
• Piptazobactam (tazocin)
• Carbapenems (imipenem, meropenem)

Usually resistant to:

• Vancomycin,
• Teicoplanin
• Metronidazole.
• Over 50% of coliform bacilli are now resistant to amoxicillin, therefore only indicated for treatment if known sensitive strain.
• Pseudomonas and Acinetobacters are resistant to amoxicillin, trimethoprim and co-amoxiclav.