Do any 2 apply?

• Temperature less than 36ºC or more than 38.3ºC
• Respiratory Rate more than 20/minute
• Heart Rate more than 90/minute
• Acutely altered mental state
• WBC >12x10⁹/L or <4x10⁹/L
• CRP >100

NO

Treat as schedule A

? need for Admission

(Minor to Moderate Infection)

YES

Do any apply?

• Systolic Blood Pressure less than 90 mm Hg
• Mean Arterial Pressure less than 65 mm Hg
• Lactate greater than 2
• Urine output < 0.5ml/kg/hr OR creatinine >177
• SpO₂ < 90%
• Platelets < 100
• INR > 1.5
• Bilirubin >34    

NO

 
(sepsis)

Treat as schedule B

Admit Patient

(Moderate to Severe Infection)

YES

(severe sepsis)

Treat as schedule C

Admit patient

Serious Life Threatening Infection – mortality ≈ 35%