Aortic Aneurysm, Femoral-Popliteal Bypass Graft, Amputation

CO-AMOXICLAV 1.2g IV single dose at induction then IV tds for 24 hours

OR

FLUCLOXACILLIN 1g IV single dose at induction then IV qds for 24 hours

plus

GENTAMICIN 1mg/kg* (max. 80mg) IV single dose at induction then IV tds for 24 hours

 
If current / previous MRSA positive:
Add

TEICOPLANIN 600mg IV at induction then 400mg at 12 and 24 hours after surgery

OR

If penicillin allergy (explanatory notes), then use:

TEICOPLANIN 600mg IV at induction then 400mg at 12 and 24 hours after surgery

Plus

GENTAMICIN 1mg/kg* (maximum of 80mg) IV single dose at induction then IV tds for 24 hours

*Add metronidazole 500mg IV tds to provide cover for anaerobic infections, particularly in patients with diabetes, gangrene or undergoing amputation