Asplenic patients are at a greater risk of developing fulminant, life-threatening sepsis and so must be appropriately vaccinated and receive antibiotic prophylaxis. The main causative organisms are:

• Streptococus pneumoniae
• Haemophilus influenzae
• Neisseria meningitidis.

Click here for Splenectomy Guideline (NOTE: current version being updated. Please contact Microbiology for advice)